Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.

In order to test the hypothesis that the general decline in gastric cancer observed in many countries is due to a selective decline in Laurén's intestinal type, we re-examined all 427 histologic sections obtained from gastric carcinomas diagnosed at the Department of Pathology, University Hospi...

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Autores principales: Lundegårdh, G., Lindgren, A., Rohul, A., Nyrén, O., Hansson, L. E., Bergström, R., Adami, H. O.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977875/
https://www.ncbi.nlm.nih.gov/pubmed/1764385
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author Lundegårdh, G.
Lindgren, A.
Rohul, A.
Nyrén, O.
Hansson, L. E.
Bergström, R.
Adami, H. O.
author_facet Lundegårdh, G.
Lindgren, A.
Rohul, A.
Nyrén, O.
Hansson, L. E.
Bergström, R.
Adami, H. O.
author_sort Lundegårdh, G.
collection PubMed
description In order to test the hypothesis that the general decline in gastric cancer observed in many countries is due to a selective decline in Laurén's intestinal type, we re-examined all 427 histologic sections obtained from gastric carcinomas diagnosed at the Department of Pathology, University Hospital, Uppsala, Sweden, in 1951, 1961, 1971-72 and 1981. The relative proportions of intestinal and diffuse type cancers were compared. The intestinal type was significantly (P less than 0.001) more common among elderly people than in the younger age groups. The relative proportions of intestinal type carcinoma in the four periods under study were 65%, 55%, 42% and 60%, respectively. The absence of any clearly discernible trend over time contradicts the hypothesis of diverse secular trends for intestinal and diffuse types of gastric carcinoma.
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spelling pubmed-19778752009-09-10 Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951. Lundegårdh, G. Lindgren, A. Rohul, A. Nyrén, O. Hansson, L. E. Bergström, R. Adami, H. O. Br J Cancer Research Article In order to test the hypothesis that the general decline in gastric cancer observed in many countries is due to a selective decline in Laurén's intestinal type, we re-examined all 427 histologic sections obtained from gastric carcinomas diagnosed at the Department of Pathology, University Hospital, Uppsala, Sweden, in 1951, 1961, 1971-72 and 1981. The relative proportions of intestinal and diffuse type cancers were compared. The intestinal type was significantly (P less than 0.001) more common among elderly people than in the younger age groups. The relative proportions of intestinal type carcinoma in the four periods under study were 65%, 55%, 42% and 60%, respectively. The absence of any clearly discernible trend over time contradicts the hypothesis of diverse secular trends for intestinal and diffuse types of gastric carcinoma. Nature Publishing Group 1991-12 /pmc/articles/PMC1977875/ /pubmed/1764385 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Lundegårdh, G.
Lindgren, A.
Rohul, A.
Nyrén, O.
Hansson, L. E.
Bergström, R.
Adami, H. O.
Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title_full Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title_fullStr Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title_full_unstemmed Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title_short Intestinal and diffuse types of gastric cancer: secular trends in Sweden since 1951.
title_sort intestinal and diffuse types of gastric cancer: secular trends in sweden since 1951.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977875/
https://www.ncbi.nlm.nih.gov/pubmed/1764385
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