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Large-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy.
A simple method for the rapid expansion of human CD4+ T cells with both helper and killer functions was established. CD4+ T cells separated from peripheral blood mononuclear cells using immunomagnetic beads were stimulated with immobilised OKT-3 monoclonal antibody (mAb) plus recombinant interleukin...
Autores principales: | Nakamura, Y., Tokuda, Y., Iwasawa, M., Tsukamoto, H., Kidokoro, M., Kobayashi, N., Kato, S., Mitomi, T., Habu, S., Nishimura, T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977880/ https://www.ncbi.nlm.nih.gov/pubmed/1353365 |
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