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In vivo measurement of the association constant of a radio-labelled monoclonal antibody in experimental immunotargeting.

Exploring the fundamental mechanisms behind the low tumour uptake of labelled monoclonal antibodies (MoAbs) during in vivo immunotargeting, experiments were performed to estimate the in vivo value of the association constant (Ka) in an experimental targeting reaction. An artificial tumour model was...

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Detalles Bibliográficos
Autores principales: Fjeld, J. G., Benestad, H. B., Stigbrand, T., Nustad, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977891/
https://www.ncbi.nlm.nih.gov/pubmed/1637680