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In vivo measurement of the association constant of a radio-labelled monoclonal antibody in experimental immunotargeting.
Exploring the fundamental mechanisms behind the low tumour uptake of labelled monoclonal antibodies (MoAbs) during in vivo immunotargeting, experiments were performed to estimate the in vivo value of the association constant (Ka) in an experimental targeting reaction. An artificial tumour model was...
Autores principales: | Fjeld, J. G., Benestad, H. B., Stigbrand, T., Nustad, K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977891/ https://www.ncbi.nlm.nih.gov/pubmed/1637680 |
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