Increased expression and mutation of p53 in choroidal melanoma.

Using CM-1 antibody directed against the human p53 protein, high levels of mutant p53 protein expression were found in 12 out of 18 malignant choroidal melanomas. In contrast, we failed to observe elevated p53 expression, indicating the absence of p53 mutation in seven choroidal naevi, a potentially...

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Detalles Bibliográficos
Autores principales: Tobal, K., Warren, W., Cooper, C. S., McCartney, A., Hungerford, J., Lightman, S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977965/
https://www.ncbi.nlm.nih.gov/pubmed/1419633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977965/
https://www.ncbi.nlm.nih.gov/pubmed/1419633

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