Variation in the gene coding for the M5 Muscarinic receptor (CHRM5) influences cigarette dose but is not associated with dependence to drugs of addiction: evidence from a prospective population based cohort study of young adults

BACKGROUND: The mesolimbic structures of the brain are important in the anticipation and perception of reward. Moreover, many drugs of addiction elicit their response in these structures. The M5 muscarinic receptor (M5R) is expressed in dopamine-containing neurones of the substantia nigra pars compa...

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Detalles Bibliográficos
Autores principales: Anney, Richard JL, Lotfi-Miri, Mehrnoush, Olsson, Craig A, Reid, Sophie C, Hemphill, Sheryl A, Patton, George C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978498/
https://www.ncbi.nlm.nih.gov/pubmed/17608938
http://dx.doi.org/10.1186/1471-2156-8-46

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