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Constraint-Based Modeling and Kinetic Analysis of the Smad Dependent TGF-β Signaling Pathway
BACKGROUND: Investigation of dynamics and regulation of the TGF-β signaling pathway is central to the understanding of complex cellular processes such as growth, apoptosis, and differentiation. In this study, we aim at using systems biology approach to provide dynamic analysis on this pathway. METHO...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978528/ https://www.ncbi.nlm.nih.gov/pubmed/17895977 http://dx.doi.org/10.1371/journal.pone.0000936 |