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Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression

BACKGROUND: In HIV-infected T lymphocytes, NF-κB/Rel transcription factors are major elements involved in the activation of LTR-dependent transcription from latency. Most NF-κB heterodimer p65/p50 is sequestered as an inactive form in the cytoplasm of resting T lymphocytes via its interaction with I...

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Detalles Bibliográficos
Autores principales: Coiras, Mayte, López-Huertas, María Rosa, Rullas, Joaquín, Mittelbrunn, Maria, Alcamí, José
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988826/
https://www.ncbi.nlm.nih.gov/pubmed/17686171
http://dx.doi.org/10.1186/1742-4690-4-56

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