Germ Line Origin and Somatic Mutations Determine the Target Tissues in Systemic AL-Amyloidosis

BACKGROUND: Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are associated with severe diseases such as Alzheimeŕs disease, prion diseases and type-2 diabetes. Light chain (AL) -amyloidosis is unique am...

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Detalles Bibliográficos
Autores principales: Enqvist, Stina, Sletten, Knut, Stevens, Fred J., Hellman, Ulf, Westermark, Per
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989140/
https://www.ncbi.nlm.nih.gov/pubmed/17912358
http://dx.doi.org/10.1371/journal.pone.0000981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989140/
https://www.ncbi.nlm.nih.gov/pubmed/17912358
http://dx.doi.org/10.1371/journal.pone.0000981

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