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Germ Line Origin and Somatic Mutations Determine the Target Tissues in Systemic AL-Amyloidosis
BACKGROUND: Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are associated with severe diseases such as Alzheimeŕs disease, prion diseases and type-2 diabetes. Light chain (AL) -amyloidosis is unique am...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1989140/ https://www.ncbi.nlm.nih.gov/pubmed/17912358 http://dx.doi.org/10.1371/journal.pone.0000981 |