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Haemoglobin C and S Role in Acquired Immunity against Plasmodium falciparum Malaria

A recently proposed mechanism of protection for haemoglobin C (HbC; β6Glu→Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes and impaired...

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Detalles Bibliográficos
Autores principales:	Verra, Federica, Simpore, Jacques, Warimwe, George M., Tetteh, Kevin K., Howard, Tevis, Osier, Faith H. A., Bancone, Germana, Avellino, Pamela, Blot, Isa, Fegan, Greg, Bull, Peter C., Williams, Thomas N., Conway, David J., Marsh, Kevin, Modiano, David
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991593/ https://www.ncbi.nlm.nih.gov/pubmed/17912355 http://dx.doi.org/10.1371/journal.pone.0000978

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