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Multiple domain insertions and losses in the evolution of the Rab prenylation complex
BACKGROUND: Rab proteins are regulators of vesicular trafficking, requiring a lipid modification for proper function, prenylation of C-terminal cysteines. This is catalysed by a complex of a catalytic heterodimer (Rab Geranylgeranyl Transferase – RabGGTase) and an accessory protein (Rab Escort Prote...
Autores principales: | Rasteiro, Rita, Pereira-Leal, Jose B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994686/ https://www.ncbi.nlm.nih.gov/pubmed/17705859 http://dx.doi.org/10.1186/1471-2148-7-140 |
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