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Multiple domain insertions and losses in the evolution of the Rab prenylation complex

BACKGROUND: Rab proteins are regulators of vesicular trafficking, requiring a lipid modification for proper function, prenylation of C-terminal cysteines. This is catalysed by a complex of a catalytic heterodimer (Rab Geranylgeranyl Transferase – RabGGTase) and an accessory protein (Rab Escort Prote...

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Detalles Bibliográficos
Autores principales: Rasteiro, Rita, Pereira-Leal, Jose B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994686/
https://www.ncbi.nlm.nih.gov/pubmed/17705859
http://dx.doi.org/10.1186/1471-2148-7-140

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