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Exploiting noise in array CGH data to improve detection of DNA copy number change
Developing effective methods for analyzing array-CGH data to detect chromosomal aberrations is very important for the diagnosis of pathogenesis of cancer and other diseases. Current analysis methods, being largely based on smoothing and/or segmentation, are not quite capable of detecting both the ab...
Autores principales: | Hu, Jing, Gao, Jian-Bo, Cao, Yinhe, Bottinger, Erwin, Zhang, Weijia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994778/ https://www.ncbi.nlm.nih.gov/pubmed/17272296 http://dx.doi.org/10.1093/nar/gkl730 |
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