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Transcriptional regulation at a glance

Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotypes and phenotypes. The transcriptional regulation process is one of the obstacles that need to be understood to bridge our...

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Detalles Bibliográficos
Autor principal: Sperling, Silke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995546/
https://www.ncbi.nlm.nih.gov/pubmed/17903283
http://dx.doi.org/10.1186/1471-2105-8-S6-S2
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author Sperling, Silke
author_facet Sperling, Silke
author_sort Sperling, Silke
collection PubMed
description Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotypes and phenotypes. The transcriptional regulation process is one of the obstacles that need to be understood to bridge our current information gap. It describes the first step from the genomic sequence information to RNA templates used for protein production or as direct functional units, like non-coding RNAs (e.g. micro RNAs). This introduction aims to highlight the key aspects of the transcriptional process from our current understanding.
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spelling pubmed-19955462007-10-02 Transcriptional regulation at a glance Sperling, Silke BMC Bioinformatics Review Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotypes and phenotypes. The transcriptional regulation process is one of the obstacles that need to be understood to bridge our current information gap. It describes the first step from the genomic sequence information to RNA templates used for protein production or as direct functional units, like non-coding RNAs (e.g. micro RNAs). This introduction aims to highlight the key aspects of the transcriptional process from our current understanding. BioMed Central 2007-09-27 /pmc/articles/PMC1995546/ /pubmed/17903283 http://dx.doi.org/10.1186/1471-2105-8-S6-S2 Text en Copyright © 2007 Sperling; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Sperling, Silke
Transcriptional regulation at a glance
title Transcriptional regulation at a glance
title_full Transcriptional regulation at a glance
title_fullStr Transcriptional regulation at a glance
title_full_unstemmed Transcriptional regulation at a glance
title_short Transcriptional regulation at a glance
title_sort transcriptional regulation at a glance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995546/
https://www.ncbi.nlm.nih.gov/pubmed/17903283
http://dx.doi.org/10.1186/1471-2105-8-S6-S2
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