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Primaquine Clears Submicroscopic Plasmodium falciparum Gametocytes that Persist after Treatment with Sulphadoxine-Pyrimethamine and Artesunate

BACKGROUND: P. falciparum gametocytes may persist after treatment with sulphadoxine-pyrimethamine (SP) plus artesunate (AS) and contribute considerably to malaria transmission. We determined the efficacy of SP+AS plus a single dose of primaquine (PQ, 0.75 mg/kg) on clearing gametocytaemia measured b...

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Detalles Bibliográficos
Autores principales:	Shekalaghe, Seif, Drakeley, Chris, Gosling, Roly, Ndaro, Arnold, van Meegeren, Monique, Enevold, Anders, Alifrangis, Michael, Mosha, Frank, Sauerwein, Robert, Bousema, Teun
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995753/ https://www.ncbi.nlm.nih.gov/pubmed/17925871 http://dx.doi.org/10.1371/journal.pone.0001023

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