Necrotising colitis related to clozapine? A rare but life threatening side effect

We report here a case of a 34-year-old gentleman who developed right-sided necrotising colitis after clozapine usage. Anticholinergic activity is believed to the cause. We believe that in patients who have been consuming medications known to have an association with necrotising colitis, constipation...

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Detalles Bibliográficos
Autores principales: Leong, Quor M, Wong, Kutt S, Koh, Dean C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997107/
https://www.ncbi.nlm.nih.gov/pubmed/17711574
http://dx.doi.org/10.1186/1749-7922-2-21
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author Leong, Quor M
Wong, Kutt S
Koh, Dean C
author_facet Leong, Quor M
Wong, Kutt S
Koh, Dean C
author_sort Leong, Quor M
collection PubMed
description We report here a case of a 34-year-old gentleman who developed right-sided necrotising colitis after clozapine usage. Anticholinergic activity is believed to the cause. We believe that in patients who have been consuming medications known to have an association with necrotising colitis, constipation with concomitant increasing abdominal pain, distension and fever should be treated with a strong index of suspicion. Consideration of necrotising colitis should prompt expeditious resection of the affected colonic segment.
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spelling pubmed-19971072007-10-02 Necrotising colitis related to clozapine? A rare but life threatening side effect Leong, Quor M Wong, Kutt S Koh, Dean C World J Emerg Surg Case Report We report here a case of a 34-year-old gentleman who developed right-sided necrotising colitis after clozapine usage. Anticholinergic activity is believed to the cause. We believe that in patients who have been consuming medications known to have an association with necrotising colitis, constipation with concomitant increasing abdominal pain, distension and fever should be treated with a strong index of suspicion. Consideration of necrotising colitis should prompt expeditious resection of the affected colonic segment. BioMed Central 2007-08-21 /pmc/articles/PMC1997107/ /pubmed/17711574 http://dx.doi.org/10.1186/1749-7922-2-21 Text en Copyright © 2007 Leong et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Leong, Quor M
Wong, Kutt S
Koh, Dean C
Necrotising colitis related to clozapine? A rare but life threatening side effect
title Necrotising colitis related to clozapine? A rare but life threatening side effect
title_full Necrotising colitis related to clozapine? A rare but life threatening side effect
title_fullStr Necrotising colitis related to clozapine? A rare but life threatening side effect
title_full_unstemmed Necrotising colitis related to clozapine? A rare but life threatening side effect
title_short Necrotising colitis related to clozapine? A rare but life threatening side effect
title_sort necrotising colitis related to clozapine? a rare but life threatening side effect
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997107/
https://www.ncbi.nlm.nih.gov/pubmed/17711574
http://dx.doi.org/10.1186/1749-7922-2-21
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AT kohdeanc necrotisingcolitisrelatedtoclozapineararebutlifethreateningsideeffect

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