Cargando…

Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

BACKGROUND: Aminopeptidase N (APN/CD13), a 150-kDa metalloprotease, is a multifunctional cell surface aminopeptidase with ubiquitous expression. Recent studies have suggested that APN/CD13 plays an important role in tumor progression of several human malignancies. In the current study, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Terauchi, Mikio, Kajiyama, Hiroaki, Shibata, Kiyosumi, Ino, Kazuhiko, Nawa, Akihiro, Mizutani, Shigehiko, Kikkawa, Fumitaka
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000898/ https://www.ncbi.nlm.nih.gov/pubmed/17655775 http://dx.doi.org/10.1186/1471-2407-7-140

Ejemplares similares

Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer
por: Tsukamoto, Hirohisa, et al.
Publicado: (2008)

P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling
por: Shibata, Kiyosumi, et al.
Publicado: (2007)

Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells
por: Koya, Yoshihiro, et al.
Publicado: (2018)

Estrogen producing ovarian fibrosarcoma: A case report
por: Miura, Mayo, et al.
Publicado: (2019)

Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
por: Hosono, S, et al.
Publicado: (2007)

Growing Teratoma Syndrome of the Ovary Showing Three Patterns of Metastasis: A Case Report
por: Shibata, Kiyosumi, et al.
Publicado: (2013)

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells
por: Yuan, Hong, et al.
Publicado: (2015)

The impact of systematic retroperitoneal lymphadenectomy on long-term oncologic outcome of women with advanced ovarian clear-cell carcinoma
por: Kajiyama, Hiroaki, et al.
Publicado: (2020)

Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells
por: Sakata, Jun, et al.
Publicado: (2017)

Placental Leucine Aminopeptidase as a Potential Specific Urine Biomarker for Invasive Ovarian Cancer
por: Matsukawa, Tetsuya, et al.
Publicado: (2021)

Clinicopathologic features of epithelial ovarian carcinoma in younger vs. older patients: analysis in Japanese women
por: Yoshikawa, Nobuhisa, et al.
Publicado: (2014)

Folate‐appended cyclodextrin carrier targets ovarian cancer cells expressing the proton‐coupled folate transporter
por: Saito, Shinichi, et al.
Publicado: (2020)

GPC3 expression in mouse ovarian cancer induces GPC3-specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth
por: LUO, CHENHONG, et al.
Publicado: (2014)

Efficacy of glypican-3-derived peptide vaccine therapy on the survival of patients with refractory ovarian clear cell carcinoma
por: Suzuki, Shiro, et al.
Publicado: (2016)

Extracellular miRNAs as Predictive Biomarkers for Glypican-3-Derived Peptide Vaccine Therapy Response in Ovarian Clear Cell Carcinoma
por: Ukai, Mayu, et al.
Publicado: (2021)

Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells
por: Niimi, Kaoru, et al.
Publicado: (2014)

Ovarian cancer‐associated mesothelial cells induce acquired platinum‐resistance in peritoneal metastasis via the FN1/Akt signaling pathway
por: Yoshihara, Masato, et al.
Publicado: (2020)

Fertility-sparing surgery and oncologic outcome among patients with early-stage ovarian cancer ~propensity score- matched analysis~
por: Kajiyama, Hiroaki, et al.
Publicado: (2019)

Significant clinical response of progressive recurrent ovarian clear cell carcinoma to glypican-3-derived peptide vaccine therapy: Two case reports
por: Suzuki, Shiro, et al.
Publicado: (2014)

Angiotensin II type 1 receptor expression in ovarian cancer and its correlation with tumour angiogenesis and patient survival
por: Ino, K, et al.
Publicado: (2006)

Expression of Aminopeptidase N on Human Choriocarcinoma Cells and Cell Growth Suppression by the Inhibition of Aminopeptidase N Activity
por: Ino, Kazuhiko, et al.
Publicado: (1994)

Comparison of prognoses according to non‐positive and positive spectrin αII expression detected immunohistochemically in epithelial ovarian carcinoma: a retrospective study.
por: Maeda, Osamu, et al.
Publicado: (2016)

KIF20A expression as a prognostic indicator and its possible involvement in the proliferation of ovarian clear-cell carcinoma cells
por: Kawai, Yosuke, et al.
Publicado: (2018)

Aminopeptidase N (APN/CD13) as a target molecule for scirrhous gastric cancer
por: Nohara, Shigeo, et al.
Publicado: (2016)

The Role of the Ectopeptidase APN/CD13 in Cancer
por: Lendeckel, Uwe, et al.
Publicado: (2023)

PRIMA-1(MET) induces apoptosis through accumulation of intracellular reactive oxygen species irrespective of p53 status and chemo-sensitivity in epithelial ovarian cancer cells
por: YOSHIKAWA, NOBUHISA, et al.
Publicado: (2016)

Survival benefit of taxane plus platinum in recurrent ovarian cancer with non-clear cell, non-mucinous histology
por: Kajiyama, Hiroaki, et al.
Publicado: (2014)

Epidemiological overview of metastatic ovarian carcinoma: long-term experience of TOTSG database
por: Kajiyama, Hiroaki, et al.
Publicado: (2019)

Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer
por: Kitami, Kazuhisa, et al.
Publicado: (2020)

Postoperative chemoradiation therapy using high dose cisplatin and fluorouracil for high- and intermediate-risk uterine cervical cancer
por: Miyauchi, Rise, et al.
Publicado: (2017)

Establishment and characterization of cell lines derived from complete hydatidiform mole
por: Yamamoto, Eiko, et al.
Publicado: (2017)

Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer
por: Ino, K, et al.
Publicado: (2006)

The balance between fetal oxytocin and placental leucine aminopeptidase (P-LAP) controls human uterine contraction around labor onset
por: Yoshihara, Masato, et al.
Publicado: (2023)

Extracellular cysteines define ectopeptidase (APN, CD13) expression and function
por: Firla, Beate, et al.
Publicado: (2002)

The possible existence of occult metastasis in patients with ovarian clear-cell carcinoma who underwent complete resection without any residual tumours
por: Kajiyama, Hiroaki, et al.
Publicado: (2018)

The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study
por: Yoshikawa, Nobuhisa, et al.
Publicado: (2020)

Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis
por: Yamamoto, E, et al.
Publicado: (2007)

Selective cytotoxicity of indirect nonequilibrium atmospheric pressure plasma against ovarian clear-cell carcinoma
por: Utsumi, Fumi, et al.
Publicado: (2014)

Long-term survival of young women receiving fertility-sparing surgery for ovarian cancer in comparison with those undergoing radical surgery
por: Kajiyama, H, et al.
Publicado: (2011)

Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?
por: Maseki, Zenta, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0s6mqgi5pt49viu9s5sksfo09o