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The in vitro effects and cross-resistance patterns of some novel anthracyclines.

A range of new anthracyclines, structurally related to adriamycin (ADM), has been synthesised and studied in vitro. Three compounds described in this paper (Ro 31-1215; Ro 31-1741; Ro 31-2035) are all 4-demethoxyanthracyclines. In the mouse mammary tumour cell line, EMT6/Ca/VJAC, using a 1 h drug ex...

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Detalles Bibliográficos
Autores principales:	Twentyman, P. R., Fox, N. E., Wright, K. A., Workman, P., Broadhurst, M. J., Martin, J. A., Bleehen, N. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1986
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001391/ https://www.ncbi.nlm.nih.gov/pubmed/3459509

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