The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.

Three hundred and four suspected cases of malignant melanoma diagnosed in Northern Ireland over a 5 year period have been reviewed. Two hundred and forty fulfilled the diagnostic criteria of invasive cutaneous malignant melanoma (CMM) and were accepted as suitable for analysis an incidence of 3.12....

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Autores principales: Gordon, L. G., Lowry, W. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1986
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001481/
https://www.ncbi.nlm.nih.gov/pubmed/3947518
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author Gordon, L. G.
Lowry, W. S.
author_facet Gordon, L. G.
Lowry, W. S.
author_sort Gordon, L. G.
collection PubMed
description Three hundred and four suspected cases of malignant melanoma diagnosed in Northern Ireland over a 5 year period have been reviewed. Two hundred and forty fulfilled the diagnostic criteria of invasive cutaneous malignant melanoma (CMM) and were accepted as suitable for analysis an incidence of 3.12. The female to male ratio for CMM in this study is 3:1. This excess of female lesions occurs at all major anatomical sites and for all tumour types. There are many thick melanomas in the province, and 67% of cases were greater than 1.7 mm thick. Each tumour type has a distinctive age curve. The implications of these findings are discussed. The evidence suggests that intrinsic factors are as important as extrinsic factors.
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spelling pubmed-20014812009-09-10 The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland. Gordon, L. G. Lowry, W. S. Br J Cancer Research Article Three hundred and four suspected cases of malignant melanoma diagnosed in Northern Ireland over a 5 year period have been reviewed. Two hundred and forty fulfilled the diagnostic criteria of invasive cutaneous malignant melanoma (CMM) and were accepted as suitable for analysis an incidence of 3.12. The female to male ratio for CMM in this study is 3:1. This excess of female lesions occurs at all major anatomical sites and for all tumour types. There are many thick melanomas in the province, and 67% of cases were greater than 1.7 mm thick. Each tumour type has a distinctive age curve. The implications of these findings are discussed. The evidence suggests that intrinsic factors are as important as extrinsic factors. Nature Publishing Group 1986-01 /pmc/articles/PMC2001481/ /pubmed/3947518 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Gordon, L. G.
Lowry, W. S.
The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title_full The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title_fullStr The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title_full_unstemmed The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title_short The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
title_sort incidence and pathogenesis of invasive cutaneous malignant melanoma in northern ireland.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001481/
https://www.ncbi.nlm.nih.gov/pubmed/3947518
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