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Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.

Two and four treatments of 5 mmol kg-1 of buthionine sulfoximine (BSO) at an interval of 12 h depleted the glutathione (GSH) content in NFSa tumours of C3H/He mice, respectively, to 24.0 and 1.78 percent of the untreated controls. BSO pre-treatments every 12 h enhanced the cytotoxicity of cyclophosp...

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Detalles Bibliográficos
Autores principales:	Ono, K., Komuro, C., Tsutsui, K., Shibamoto, Y., Nishidai, T., Takahashi, M., Abe, M., Shrieve, D. C.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1986
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001553/ https://www.ncbi.nlm.nih.gov/pubmed/3801271

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