Hodgkin's disease: case control epidemiological study in Yorkshire.

This is the first report of a case-control epidemiological study on lymphomas and leukaemias occurring in Yorkshire during 1979-84. This paper deals with the results of the Hodgkin's disease analysis comprising 248 cases and 489 controls. The results indicate support for previous work with resp...

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Detalles Bibliográficos
Autores principales: Bernard, S. M., Cartwright, R. A., Darwin, C. M., Richards, I. D., Roberts, B., O'Brien, C., Bird, C. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001560/
https://www.ncbi.nlm.nih.gov/pubmed/3814482
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author Bernard, S. M.
Cartwright, R. A.
Darwin, C. M.
Richards, I. D.
Roberts, B.
O'Brien, C.
Bird, C. C.
author_facet Bernard, S. M.
Cartwright, R. A.
Darwin, C. M.
Richards, I. D.
Roberts, B.
O'Brien, C.
Bird, C. C.
author_sort Bernard, S. M.
collection PubMed
description This is the first report of a case-control epidemiological study on lymphomas and leukaemias occurring in Yorkshire during 1979-84. This paper deals with the results of the Hodgkin's disease analysis comprising 248 cases and 489 controls. The results indicate support for previous work with respect to small family size and past history of infectious mononucleosis. Positive observations made in a previous pilot study are also confirmed and extended with respect to associations with certain chronic skin lesions, dental anaesthesia and familial factors. Negative associations are described with respect to X-ray exposures and cigarette smoking. It is proposed that these results fit into a general hypothesis that these conditions are the result of interaction between infectious agents and altered immunity in those persons genetically predisposed.
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spelling pubmed-20015602009-09-10 Hodgkin's disease: case control epidemiological study in Yorkshire. Bernard, S. M. Cartwright, R. A. Darwin, C. M. Richards, I. D. Roberts, B. O'Brien, C. Bird, C. C. Br J Cancer Research Article This is the first report of a case-control epidemiological study on lymphomas and leukaemias occurring in Yorkshire during 1979-84. This paper deals with the results of the Hodgkin's disease analysis comprising 248 cases and 489 controls. The results indicate support for previous work with respect to small family size and past history of infectious mononucleosis. Positive observations made in a previous pilot study are also confirmed and extended with respect to associations with certain chronic skin lesions, dental anaesthesia and familial factors. Negative associations are described with respect to X-ray exposures and cigarette smoking. It is proposed that these results fit into a general hypothesis that these conditions are the result of interaction between infectious agents and altered immunity in those persons genetically predisposed. Nature Publishing Group 1987-01 /pmc/articles/PMC2001560/ /pubmed/3814482 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Bernard, S. M.
Cartwright, R. A.
Darwin, C. M.
Richards, I. D.
Roberts, B.
O'Brien, C.
Bird, C. C.
Hodgkin's disease: case control epidemiological study in Yorkshire.
title Hodgkin's disease: case control epidemiological study in Yorkshire.
title_full Hodgkin's disease: case control epidemiological study in Yorkshire.
title_fullStr Hodgkin's disease: case control epidemiological study in Yorkshire.
title_full_unstemmed Hodgkin's disease: case control epidemiological study in Yorkshire.
title_short Hodgkin's disease: case control epidemiological study in Yorkshire.
title_sort hodgkin's disease: case control epidemiological study in yorkshire.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001560/
https://www.ncbi.nlm.nih.gov/pubmed/3814482
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