Cargando…

Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.

A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasleton, P. S., Gomm, S., Blair, V., Thatcher, N.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1986
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001595/
https://www.ncbi.nlm.nih.gov/pubmed/3801292
_version_ 1782135637226291200
author Hasleton, P. S.
Gomm, S.
Blair, V.
Thatcher, N.
author_facet Hasleton, P. S.
Gomm, S.
Blair, V.
Thatcher, N.
author_sort Hasleton, P. S.
collection PubMed
description A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen. IMAGES:
format Text
id pubmed-2001595
institution National Center for Biotechnology Information
language English
publishDate 1986
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20015952009-09-10 Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. Hasleton, P. S. Gomm, S. Blair, V. Thatcher, N. Br J Cancer Research Article A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen. IMAGES: Nature Publishing Group 1986-12 /pmc/articles/PMC2001595/ /pubmed/3801292 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Hasleton, P. S.
Gomm, S.
Blair, V.
Thatcher, N.
Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title_full Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title_fullStr Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title_full_unstemmed Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title_short Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
title_sort pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001595/
https://www.ncbi.nlm.nih.gov/pubmed/3801292
work_keys_str_mv AT hasletonps pulmonarycarcinoidtumoursaclinicopathologicalstudyof35cases
AT gomms pulmonarycarcinoidtumoursaclinicopathologicalstudyof35cases
AT blairv pulmonarycarcinoidtumoursaclinicopathologicalstudyof35cases
AT thatchern pulmonarycarcinoidtumoursaclinicopathologicalstudyof35cases