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Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases.
A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1986
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001595/ https://www.ncbi.nlm.nih.gov/pubmed/3801292 |
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author | Hasleton, P. S. Gomm, S. Blair, V. Thatcher, N. |
author_facet | Hasleton, P. S. Gomm, S. Blair, V. Thatcher, N. |
author_sort | Hasleton, P. S. |
collection | PubMed |
description | A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen. IMAGES: |
format | Text |
id | pubmed-2001595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1986 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20015952009-09-10 Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. Hasleton, P. S. Gomm, S. Blair, V. Thatcher, N. Br J Cancer Research Article A clinico-pathological study of 35 bronchial carcinoid tumours was undertaken. Age, T stage, N stage, lymph node involvement, number of lymph nodes involved and number of cigarettes smoked per day were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessing the prognosis. However there was a tendency for a well differentiated neuroendocrine carcinoma to stain strongly in some areas with carcinoembryonic antigen. IMAGES: Nature Publishing Group 1986-12 /pmc/articles/PMC2001595/ /pubmed/3801292 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Hasleton, P. S. Gomm, S. Blair, V. Thatcher, N. Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title | Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title_full | Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title_fullStr | Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title_full_unstemmed | Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title_short | Pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
title_sort | pulmonary carcinoid tumours: a clinico-pathological study of 35 cases. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001595/ https://www.ncbi.nlm.nih.gov/pubmed/3801292 |
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