Cargando…
Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire.
This is the second report of a large case control study of lymphoma/leukaemia occurring in Yorkshire during 1979-84, and deals with chronic lymphocytic leukaemia presenting either in its haematological (CLL) or more solid lymphomatous (malignant lymphoma-lymphocytic or MLL) forms. In all, 330 cases...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1987
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001663/ https://www.ncbi.nlm.nih.gov/pubmed/3304389 |
| _version_ | 1782135650844147712 |
|---|---|
| author | Cartwright, R. A. Bernard, S. M. Bird, C. C. Darwin, C. M. O'Brien, C. Richards, I. D. Roberts, B. McKinney, P. A. |
| author_facet | Cartwright, R. A. Bernard, S. M. Bird, C. C. Darwin, C. M. O'Brien, C. Richards, I. D. Roberts, B. McKinney, P. A. |
| author_sort | Cartwright, R. A. |
| collection | PubMed |
| description | This is the second report of a large case control study of lymphoma/leukaemia occurring in Yorkshire during 1979-84, and deals with chronic lymphocytic leukaemia presenting either in its haematological (CLL) or more solid lymphomatous (malignant lymphoma-lymphocytic or MLL) forms. In all, 330 cases and 561 controls were interviewed. The results support the concept that CLL/MLL is a condition of multiple aetiologies with evidence for genetic predisposition through an excess of family cases, immune perturbation demonstrated by excessive previous skin diseases and phenylbutazone use, and viral involvement shown by links with infectious diseases and multiple sclerosis. |
| format | Text |
| id | pubmed-2001663 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1987 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-20016632009-09-10 Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. Cartwright, R. A. Bernard, S. M. Bird, C. C. Darwin, C. M. O'Brien, C. Richards, I. D. Roberts, B. McKinney, P. A. Br J Cancer Research Article This is the second report of a large case control study of lymphoma/leukaemia occurring in Yorkshire during 1979-84, and deals with chronic lymphocytic leukaemia presenting either in its haematological (CLL) or more solid lymphomatous (malignant lymphoma-lymphocytic or MLL) forms. In all, 330 cases and 561 controls were interviewed. The results support the concept that CLL/MLL is a condition of multiple aetiologies with evidence for genetic predisposition through an excess of family cases, immune perturbation demonstrated by excessive previous skin diseases and phenylbutazone use, and viral involvement shown by links with infectious diseases and multiple sclerosis. Nature Publishing Group 1987-07 /pmc/articles/PMC2001663/ /pubmed/3304389 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Research Article Cartwright, R. A. Bernard, S. M. Bird, C. C. Darwin, C. M. O'Brien, C. Richards, I. D. Roberts, B. McKinney, P. A. Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title | Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title_full | Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title_fullStr | Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title_full_unstemmed | Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title_short | Chronic lymphocytic leukaemia: case control epidemiological study in Yorkshire. |
| title_sort | chronic lymphocytic leukaemia: case control epidemiological study in yorkshire. |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001663/ https://www.ncbi.nlm.nih.gov/pubmed/3304389 |
| work_keys_str_mv | AT cartwrightra chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT bernardsm chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT birdcc chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT darwincm chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT obrienc chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT richardsid chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT robertsb chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire AT mckinneypa chroniclymphocyticleukaemiacasecontrolepidemiologicalstudyinyorkshire |