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Recombinant human interferon alpha increases oestrogen receptor expression in human breast cancer cells (ZR-75-1) and sensitizes them to the anti-proliferative effects of tamoxifen.
Exposure of ZR-75-1 human breast cancer cells for 48 h to human recombinant interferon alpha (IFN alpha) resulted in increased expression of oestrogen receptors as measured in a whole cell binding assay. This effect was inversely proportional to dose being significant following treatment with 10-100...
Autores principales: | van den Berg, H. W., Leahey, W. J., Lynch, M., Clarke, R., Nelson, J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001764/ https://www.ncbi.nlm.nih.gov/pubmed/3567059 |
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