Cargando…
Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours.
Polyclonal antibodies have been raised in rabbits to a haemocyanin adduct of a reductively-activated, fluorinated analogue of misonidazole. Fluorescence immunohistochemical studies show that the polyclonal antibodies bind to spheroid sections and tumour sections in patterns similar to those revealed...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1987
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001823/ https://www.ncbi.nlm.nih.gov/pubmed/3689657 |
| _version_ | 1782135674553499648 |
|---|---|
| author | Raleigh, J. A. Miller, G. G. Franko, A. J. Koch, C. J. Fuciarelli, A. F. Kelly, D. A. |
| author_facet | Raleigh, J. A. Miller, G. G. Franko, A. J. Koch, C. J. Fuciarelli, A. F. Kelly, D. A. |
| author_sort | Raleigh, J. A. |
| collection | PubMed |
| description | Polyclonal antibodies have been raised in rabbits to a haemocyanin adduct of a reductively-activated, fluorinated analogue of misonidazole. Fluorescence immunohistochemical studies show that the polyclonal antibodies bind to spheroid sections and tumour sections in patterns similar to those revealed by autoradiographic studies with a tritium-labelled derivative of the fluorinated misonidazole analogue. IMAGES: |
| format | Text |
| id | pubmed-2001823 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1987 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-20018232009-09-10 Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. Raleigh, J. A. Miller, G. G. Franko, A. J. Koch, C. J. Fuciarelli, A. F. Kelly, D. A. Br J Cancer Research Article Polyclonal antibodies have been raised in rabbits to a haemocyanin adduct of a reductively-activated, fluorinated analogue of misonidazole. Fluorescence immunohistochemical studies show that the polyclonal antibodies bind to spheroid sections and tumour sections in patterns similar to those revealed by autoradiographic studies with a tritium-labelled derivative of the fluorinated misonidazole analogue. IMAGES: Nature Publishing Group 1987-10 /pmc/articles/PMC2001823/ /pubmed/3689657 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Research Article Raleigh, J. A. Miller, G. G. Franko, A. J. Koch, C. J. Fuciarelli, A. F. Kelly, D. A. Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title | Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title_full | Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title_fullStr | Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title_full_unstemmed | Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title_short | Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| title_sort | fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001823/ https://www.ncbi.nlm.nih.gov/pubmed/3689657 |
| work_keys_str_mv | AT raleighja fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours AT millergg fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours AT frankoaj fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours AT kochcj fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours AT fuciarelliaf fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours AT kellyda fluorescenceimmunohistochemicaldetectionofhypoxiccellsinspheroidsandtumours |