Confirmation of a prognostic index in primary breast cancer.

A prognostic index, previously derived in a group of 387 patients with primary breast cancer, has been recalculated for the same patients with over 5 years further follow-up and shown to be unchanged. The prognostic index has also been applied prospectively to a further group of 320 patients and sho...

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Autores principales: Todd, J. H., Dowle, C., Williams, M. R., Elston, C. W., Ellis, I. O., Hinton, C. P., Blamey, R. W., Haybittle, J. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001834/
https://www.ncbi.nlm.nih.gov/pubmed/3689666
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author Todd, J. H.
Dowle, C.
Williams, M. R.
Elston, C. W.
Ellis, I. O.
Hinton, C. P.
Blamey, R. W.
Haybittle, J. L.
author_facet Todd, J. H.
Dowle, C.
Williams, M. R.
Elston, C. W.
Ellis, I. O.
Hinton, C. P.
Blamey, R. W.
Haybittle, J. L.
author_sort Todd, J. H.
collection PubMed
description A prognostic index, previously derived in a group of 387 patients with primary breast cancer, has been recalculated for the same patients with over 5 years further follow-up and shown to be unchanged. The prognostic index has also been applied prospectively to a further group of 320 patients and shown to be similarly effective in identifying patients with either a very good or a very poor prognosis. It has been verified that the index applies to patients with primary breast cancer. Patients have now been divided into 5 prognostic groups, predicting 11% of patients with an almost normal survival and a further 10% with a very poor prognosis. The index is used to stratify patients to study the effects of treatment regimes within groups of similar patients.
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spelling pubmed-20018342009-09-10 Confirmation of a prognostic index in primary breast cancer. Todd, J. H. Dowle, C. Williams, M. R. Elston, C. W. Ellis, I. O. Hinton, C. P. Blamey, R. W. Haybittle, J. L. Br J Cancer Research Article A prognostic index, previously derived in a group of 387 patients with primary breast cancer, has been recalculated for the same patients with over 5 years further follow-up and shown to be unchanged. The prognostic index has also been applied prospectively to a further group of 320 patients and shown to be similarly effective in identifying patients with either a very good or a very poor prognosis. It has been verified that the index applies to patients with primary breast cancer. Patients have now been divided into 5 prognostic groups, predicting 11% of patients with an almost normal survival and a further 10% with a very poor prognosis. The index is used to stratify patients to study the effects of treatment regimes within groups of similar patients. Nature Publishing Group 1987-10 /pmc/articles/PMC2001834/ /pubmed/3689666 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Todd, J. H.
Dowle, C.
Williams, M. R.
Elston, C. W.
Ellis, I. O.
Hinton, C. P.
Blamey, R. W.
Haybittle, J. L.
Confirmation of a prognostic index in primary breast cancer.
title Confirmation of a prognostic index in primary breast cancer.
title_full Confirmation of a prognostic index in primary breast cancer.
title_fullStr Confirmation of a prognostic index in primary breast cancer.
title_full_unstemmed Confirmation of a prognostic index in primary breast cancer.
title_short Confirmation of a prognostic index in primary breast cancer.
title_sort confirmation of a prognostic index in primary breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001834/
https://www.ncbi.nlm.nih.gov/pubmed/3689666
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