Effects of glutathione depletion on the cytotoxicity of agents toward a human colonic tumour cell line.

Levels of glutathione (GSH) in tumour tissue may be important in determining the clinical response to certain anticancer agents. Recent reports have suggested that D,L-buthionine-S,R-sulphoximine (BSO), a specific inhibitor of GSH synthesis, may be used to deplete tumour cell GSH and thus increase t...

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Detalles Bibliográficos
Autores principales: Jordan, J., d'Arcy Doherty, M., Cohen, G. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002042/
https://www.ncbi.nlm.nih.gov/pubmed/3620304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002042/
https://www.ncbi.nlm.nih.gov/pubmed/3620304

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