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Effects of glutathione depletion on the cytotoxicity of agents toward a human colonic tumour cell line.

Levels of glutathione (GSH) in tumour tissue may be important in determining the clinical response to certain anticancer agents. Recent reports have suggested that D,L-buthionine-S,R-sulphoximine (BSO), a specific inhibitor of GSH synthesis, may be used to deplete tumour cell GSH and thus increase t...

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Detalles Bibliográficos
Autores principales:	Jordan, J., d'Arcy Doherty, M., Cohen, G. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1987
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002042/ https://www.ncbi.nlm.nih.gov/pubmed/3620304

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