Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.

The relationship to survival after first recurrence of oestrogen receptor (ER), nodal status and TNM stage at diagnosis, and treatment for advanced disease was studied in 457 females whose primary breast cancer was diagnosed in 1975 to 1981. Receptor concentration was the most important predictor of...

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Detalles Bibliográficos
Autores principales: Shek, L. L., Godolphin, W., Spinelli, J. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002407/
https://www.ncbi.nlm.nih.gov/pubmed/3435707
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author Shek, L. L.
Godolphin, W.
Spinelli, J. J.
author_facet Shek, L. L.
Godolphin, W.
Spinelli, J. J.
author_sort Shek, L. L.
collection PubMed
description The relationship to survival after first recurrence of oestrogen receptor (ER), nodal status and TNM stage at diagnosis, and treatment for advanced disease was studied in 457 females whose primary breast cancer was diagnosed in 1975 to 1981. Receptor concentration was the most important predictor of post-recurrence survival, with some additional information conveyed by nodal status. ER predicted survival after recurrence independently of nodal status, clinical stage or mode of therapy. Response to endocrine therapy is only a facet of the generally favourable prognosis of ER positive patients, rather than the sole explanation.
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spelling pubmed-20024072009-09-10 Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients. Shek, L. L. Godolphin, W. Spinelli, J. J. Br J Cancer Research Article The relationship to survival after first recurrence of oestrogen receptor (ER), nodal status and TNM stage at diagnosis, and treatment for advanced disease was studied in 457 females whose primary breast cancer was diagnosed in 1975 to 1981. Receptor concentration was the most important predictor of post-recurrence survival, with some additional information conveyed by nodal status. ER predicted survival after recurrence independently of nodal status, clinical stage or mode of therapy. Response to endocrine therapy is only a facet of the generally favourable prognosis of ER positive patients, rather than the sole explanation. Nature Publishing Group 1987-12 /pmc/articles/PMC2002407/ /pubmed/3435707 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Shek, L. L.
Godolphin, W.
Spinelli, J. J.
Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title_full Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title_fullStr Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title_full_unstemmed Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title_short Oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
title_sort oestrogen receptors, nodes and stage as predictors of post-recurrence survival in 457 breast cancer patients.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002407/
https://www.ncbi.nlm.nih.gov/pubmed/3435707
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