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Histology in Breast Cancer Prognosis
Histological sections of the primary tumour and of homolateral axillary lymph nodes from 500 women with operable invasive breast cancer have been examined. The tumours have been graded and the degree of round cell infiltration assessed. These features, together with clinical palpability and patholog...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1972
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008433/ https://www.ncbi.nlm.nih.gov/pubmed/4114100 |
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author | Champion, H. R. Wallace, I. W. J. Prescott, R. J. |
author_facet | Champion, H. R. Wallace, I. W. J. Prescott, R. J. |
author_sort | Champion, H. R. |
collection | PubMed |
description | Histological sections of the primary tumour and of homolateral axillary lymph nodes from 500 women with operable invasive breast cancer have been examined. The tumours have been graded and the degree of round cell infiltration assessed. These features, together with clinical palpability and pathological involvement of axillary nodes, have been related to survival. It was found that prognosis was worse in patients with a high grade tumour and in those with histological evidence of axillary node spread. Round cell infiltration of the primary tumour did not confer improved survival. The clinical state of the axillary nodes was associated with prognosis in so far that palpable nodes were twice as commonly the seat of metastatic spread as were impalpable nodes. |
format | Text |
id | pubmed-2008433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1972 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20084332009-09-10 Histology in Breast Cancer Prognosis Champion, H. R. Wallace, I. W. J. Prescott, R. J. Br J Cancer Articles Histological sections of the primary tumour and of homolateral axillary lymph nodes from 500 women with operable invasive breast cancer have been examined. The tumours have been graded and the degree of round cell infiltration assessed. These features, together with clinical palpability and pathological involvement of axillary nodes, have been related to survival. It was found that prognosis was worse in patients with a high grade tumour and in those with histological evidence of axillary node spread. Round cell infiltration of the primary tumour did not confer improved survival. The clinical state of the axillary nodes was associated with prognosis in so far that palpable nodes were twice as commonly the seat of metastatic spread as were impalpable nodes. Nature Publishing Group 1972-04 /pmc/articles/PMC2008433/ /pubmed/4114100 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Articles Champion, H. R. Wallace, I. W. J. Prescott, R. J. Histology in Breast Cancer Prognosis |
title | Histology in Breast Cancer Prognosis |
title_full | Histology in Breast Cancer Prognosis |
title_fullStr | Histology in Breast Cancer Prognosis |
title_full_unstemmed | Histology in Breast Cancer Prognosis |
title_short | Histology in Breast Cancer Prognosis |
title_sort | histology in breast cancer prognosis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008433/ https://www.ncbi.nlm.nih.gov/pubmed/4114100 |
work_keys_str_mv | AT championhr histologyinbreastcancerprognosis AT wallaceiwj histologyinbreastcancerprognosis AT prescottrj histologyinbreastcancerprognosis |