Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane

Six out of 120 rats fed dioxane in drinking water at levels of 0.75, 1.0, 1.4 or 1.8% developed carcinomas in the nasal cavity. Spontaneous tumors at this tissue localization have not been reported to occur in laboratory animals. The carcinomas were pre-eminently of epidermoid type with few adenocar...

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Autores principales: Hoch-Ligeti, Cornelia, Argus, Mary F., Arcos, J. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008516/
https://www.ncbi.nlm.nih.gov/pubmed/4316974
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author Hoch-Ligeti, Cornelia
Argus, Mary F.
Arcos, J. C.
author_facet Hoch-Ligeti, Cornelia
Argus, Mary F.
Arcos, J. C.
author_sort Hoch-Ligeti, Cornelia
collection PubMed
description Six out of 120 rats fed dioxane in drinking water at levels of 0.75, 1.0, 1.4 or 1.8% developed carcinomas in the nasal cavity. Spontaneous tumors at this tissue localization have not been reported to occur in laboratory animals. The carcinomas were pre-eminently of epidermoid type with few adenocarcinomatous areas and epithelial papillomas. Four rats with carcinoma of the nasal cavity had hepatocellular carcinoma in addition. IMAGES:
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spelling pubmed-20085162009-09-10 Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane Hoch-Ligeti, Cornelia Argus, Mary F. Arcos, J. C. Br J Cancer Articles Six out of 120 rats fed dioxane in drinking water at levels of 0.75, 1.0, 1.4 or 1.8% developed carcinomas in the nasal cavity. Spontaneous tumors at this tissue localization have not been reported to occur in laboratory animals. The carcinomas were pre-eminently of epidermoid type with few adenocarcinomatous areas and epithelial papillomas. Four rats with carcinoma of the nasal cavity had hepatocellular carcinoma in addition. IMAGES: Nature Publishing Group 1970-03 /pmc/articles/PMC2008516/ /pubmed/4316974 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Hoch-Ligeti, Cornelia
Argus, Mary F.
Arcos, J. C.
Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title_full Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title_fullStr Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title_full_unstemmed Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title_short Induction of Carcinomas in the Nasal Cavity of Rats by Dioxane
title_sort induction of carcinomas in the nasal cavity of rats by dioxane
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008516/
https://www.ncbi.nlm.nih.gov/pubmed/4316974
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