Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis

Fifty-three biopsies from the oral mucosa in 51 Indian villagers with oral submucous fibrosis have been studied for epithelial changes. A marked atrophy of the epithelium was found in 71.7%; the atrophic epithelium showed no rete ridges. The normally unkeratinized buccal mucosa revealed either ortho...

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Autores principales: Pindborg, J. J., Mehta, F. S., Daftary, D. K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008591/
https://www.ncbi.nlm.nih.gov/pubmed/5451568
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author Pindborg, J. J.
Mehta, F. S.
Daftary, D. K.
author_facet Pindborg, J. J.
Mehta, F. S.
Daftary, D. K.
author_sort Pindborg, J. J.
collection PubMed
description Fifty-three biopsies from the oral mucosa in 51 Indian villagers with oral submucous fibrosis have been studied for epithelial changes. A marked atrophy of the epithelium was found in 71.7%; the atrophic epithelium showed no rete ridges. The normally unkeratinized buccal mucosa revealed either ortho- or parakeratosis or hyperortho- or hyperparakeratosis in 48.0%. In one patient the histologic examination disclosed a squamous cell carcinoma. In 22.6% an epithelial atypia was found. The histologic features in these atypias are compared with those seen in leukoplakias from the same survey. The possible precancerous nature of submucous fibrosis is discussed. IMAGES:
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spelling pubmed-20085912009-09-10 Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis Pindborg, J. J. Mehta, F. S. Daftary, D. K. Br J Cancer Articles Fifty-three biopsies from the oral mucosa in 51 Indian villagers with oral submucous fibrosis have been studied for epithelial changes. A marked atrophy of the epithelium was found in 71.7%; the atrophic epithelium showed no rete ridges. The normally unkeratinized buccal mucosa revealed either ortho- or parakeratosis or hyperortho- or hyperparakeratosis in 48.0%. In one patient the histologic examination disclosed a squamous cell carcinoma. In 22.6% an epithelial atypia was found. The histologic features in these atypias are compared with those seen in leukoplakias from the same survey. The possible precancerous nature of submucous fibrosis is discussed. IMAGES: Nature Publishing Group 1970-06 /pmc/articles/PMC2008591/ /pubmed/5451568 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Pindborg, J. J.
Mehta, F. S.
Daftary, D. K.
Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title_full Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title_fullStr Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title_full_unstemmed Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title_short Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
title_sort occurrence of epithelial atypia in 51 indian villagers with oral submucous fibrosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008591/
https://www.ncbi.nlm.nih.gov/pubmed/5451568
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