Tumorigenic Effect of Thioacetamide in Swiss Strain Mice

Male and female Swiss strain mice were put on a 0.03% thioacetamide diet at the age of 2 months. Control mice were kept on a stock diet. Control and treated mice were killed at the ages of 6, 9, 13 and 17 months. Progressive morphological, histological and biochemical alterations in the liver and tu...

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Detalles Bibliográficos
Autores principales: Gothoskar, S. V., Talwalkar, G. V., Bhide, S. V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008597/
https://www.ncbi.nlm.nih.gov/pubmed/4319940
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author Gothoskar, S. V.
Talwalkar, G. V.
Bhide, S. V.
author_facet Gothoskar, S. V.
Talwalkar, G. V.
Bhide, S. V.
author_sort Gothoskar, S. V.
collection PubMed
description Male and female Swiss strain mice were put on a 0.03% thioacetamide diet at the age of 2 months. Control mice were kept on a stock diet. Control and treated mice were killed at the ages of 6, 9, 13 and 17 months. Progressive morphological, histological and biochemical alterations in the liver and tumour tissue of the treated mice were studied. In the 17-month-old group, 12 out of 13 treated mice developed hepatomas. IMAGES:
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spelling pubmed-20085972009-09-10 Tumorigenic Effect of Thioacetamide in Swiss Strain Mice Gothoskar, S. V. Talwalkar, G. V. Bhide, S. V. Br J Cancer Articles Male and female Swiss strain mice were put on a 0.03% thioacetamide diet at the age of 2 months. Control mice were kept on a stock diet. Control and treated mice were killed at the ages of 6, 9, 13 and 17 months. Progressive morphological, histological and biochemical alterations in the liver and tumour tissue of the treated mice were studied. In the 17-month-old group, 12 out of 13 treated mice developed hepatomas. IMAGES: Nature Publishing Group 1970-09 /pmc/articles/PMC2008597/ /pubmed/4319940 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Gothoskar, S. V.
Talwalkar, G. V.
Bhide, S. V.
Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title_full Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title_fullStr Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title_full_unstemmed Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title_short Tumorigenic Effect of Thioacetamide in Swiss Strain Mice
title_sort tumorigenic effect of thioacetamide in swiss strain mice
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008597/
https://www.ncbi.nlm.nih.gov/pubmed/4319940
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