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Reversal of Methotrexate Toxicity in Mice by 5-Methyltetrahydrofolic Acid

1. Mice have been compeletly protected against the lethal effects of repeated injections of methotrexate by 5-methyltetrahydrofolic acid. Methotrexate-resistant cells probably owe their resistance to their high content of this substance. 2. Daily small doses were much more effective than fewer but l...

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Detalles Bibliográficos
Autores principales:	Blair, J. A., Searle, C. E.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1970
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008620/ https://www.ncbi.nlm.nih.gov/pubmed/5312191

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