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Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neith...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1970
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008624/ https://www.ncbi.nlm.nih.gov/pubmed/4319943 |
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author | Lee, Audrey E. |
author_facet | Lee, Audrey E. |
author_sort | Lee, Audrey E. |
collection | PubMed |
description | BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neither hormone treatment nor ectopic pituitaries succeeded in producing tumours as early as they appear in breeding females. |
format | Text |
id | pubmed-2008624 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1970 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20086242009-09-10 Mammary Tumour Development in BR6 Mice: Hormonal Stimulation Lee, Audrey E. Br J Cancer Articles BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neither hormone treatment nor ectopic pituitaries succeeded in producing tumours as early as they appear in breeding females. Nature Publishing Group 1970-09 /pmc/articles/PMC2008624/ /pubmed/4319943 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Articles Lee, Audrey E. Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title | Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title_full | Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title_fullStr | Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title_full_unstemmed | Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title_short | Mammary Tumour Development in BR6 Mice: Hormonal Stimulation |
title_sort | mammary tumour development in br6 mice: hormonal stimulation |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008624/ https://www.ncbi.nlm.nih.gov/pubmed/4319943 |
work_keys_str_mv | AT leeaudreye mammarytumourdevelopmentinbr6micehormonalstimulation |