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Mammary Tumour Development in BR6 Mice: Hormonal Stimulation

BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neith...

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Detalles Bibliográficos
Autor principal: Lee, Audrey E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008624/
https://www.ncbi.nlm.nih.gov/pubmed/4319943
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author Lee, Audrey E.
author_facet Lee, Audrey E.
author_sort Lee, Audrey E.
collection PubMed
description BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neither hormone treatment nor ectopic pituitaries succeeded in producing tumours as early as they appear in breeding females.
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spelling pubmed-20086242009-09-10 Mammary Tumour Development in BR6 Mice: Hormonal Stimulation Lee, Audrey E. Br J Cancer Articles BR6 female mice treated with a mixture of hormones, developed mammary tumours earlier than untreated virgin animals. Implantation of ectopic pituitaries also increased tumour incidence and reduced the age at which tumours first appeared. This effect was obtained even in the absence of ovaries. Neither hormone treatment nor ectopic pituitaries succeeded in producing tumours as early as they appear in breeding females. Nature Publishing Group 1970-09 /pmc/articles/PMC2008624/ /pubmed/4319943 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Lee, Audrey E.
Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title_full Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title_fullStr Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title_full_unstemmed Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title_short Mammary Tumour Development in BR6 Mice: Hormonal Stimulation
title_sort mammary tumour development in br6 mice: hormonal stimulation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008624/
https://www.ncbi.nlm.nih.gov/pubmed/4319943
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