Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours

The effect of pre-treatment with Corynebacterium parvum on the growth in vivo of a range of experimental mouse tumours with differing characteristics has been investigated. Varying degrees of protection were observed which were generally greater with the more immunogenic tumours. Administration of C...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, S. E., Scott, M. T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1972
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008632/
https://www.ncbi.nlm.nih.gov/pubmed/4343677
_version_ 1782135955771097088
author Smith, S. E.
Scott, M. T.
author_facet Smith, S. E.
Scott, M. T.
author_sort Smith, S. E.
collection PubMed
description The effect of pre-treatment with Corynebacterium parvum on the growth in vivo of a range of experimental mouse tumours with differing characteristics has been investigated. Varying degrees of protection were observed which were generally greater with the more immunogenic tumours. Administration of C. parvum 7 days before immunization with irradiated tumour cells diminished the protective effect which could be obtained by immunization alone. The possible basis for these seemingly conflicting influences is considered.
format Text
id pubmed-2008632
institution National Center for Biotechnology Information
language English
publishDate 1972
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20086322009-09-10 Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours Smith, S. E. Scott, M. T. Br J Cancer Articles The effect of pre-treatment with Corynebacterium parvum on the growth in vivo of a range of experimental mouse tumours with differing characteristics has been investigated. Varying degrees of protection were observed which were generally greater with the more immunogenic tumours. Administration of C. parvum 7 days before immunization with irradiated tumour cells diminished the protective effect which could be obtained by immunization alone. The possible basis for these seemingly conflicting influences is considered. Nature Publishing Group 1972-10 /pmc/articles/PMC2008632/ /pubmed/4343677 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Smith, S. E.
Scott, M. T.
Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title_full Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title_fullStr Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title_full_unstemmed Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title_short Biological Effects of Corynebacterium Parvum. III. amplification of resistance and impairment of Active Immunity to Murine Tumours
title_sort biological effects of corynebacterium parvum. iii. amplification of resistance and impairment of active immunity to murine tumours
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008632/
https://www.ncbi.nlm.nih.gov/pubmed/4343677
work_keys_str_mv AT smithse biologicaleffectsofcorynebacteriumparvumiiiamplificationofresistanceandimpairmentofactiveimmunitytomurinetumours
AT scottmt biologicaleffectsofcorynebacteriumparvumiiiamplificationofresistanceandimpairmentofactiveimmunitytomurinetumours

Ejemplares similares