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Iron Metabolism in Hodgkin's Disease

An evaluation of iron metabolism has been carried out in 23 untreated patients with Hodgkin's disease and 6 patients with other lymphomata. The reduction in red cell life span is related to the stage of the disease. There is an almost universal impairment of iron release from the reticuloendoth...

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Detalles Bibliográficos
Autores principales: Beamish, M. R., Jones, P. Ashley, Trevett, D., Evans, I. Howell, Jacobs, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1972
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008667/
https://www.ncbi.nlm.nih.gov/pubmed/4567182
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author Beamish, M. R.
Jones, P. Ashley
Trevett, D.
Evans, I. Howell
Jacobs, A.
author_facet Beamish, M. R.
Jones, P. Ashley
Trevett, D.
Evans, I. Howell
Jacobs, A.
author_sort Beamish, M. R.
collection PubMed
description An evaluation of iron metabolism has been carried out in 23 untreated patients with Hodgkin's disease and 6 patients with other lymphomata. The reduction in red cell life span is related to the stage of the disease. There is an almost universal impairment of iron release from the reticuloendothelial system with a consequent sideropenia and failure of iron delivery to the bone marrow for erythropoiesis. This defect is found in all stages of the disease and is not related to systemic symptoms.
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spelling pubmed-20086672009-09-10 Iron Metabolism in Hodgkin's Disease Beamish, M. R. Jones, P. Ashley Trevett, D. Evans, I. Howell Jacobs, A. Br J Cancer Articles An evaluation of iron metabolism has been carried out in 23 untreated patients with Hodgkin's disease and 6 patients with other lymphomata. The reduction in red cell life span is related to the stage of the disease. There is an almost universal impairment of iron release from the reticuloendothelial system with a consequent sideropenia and failure of iron delivery to the bone marrow for erythropoiesis. This defect is found in all stages of the disease and is not related to systemic symptoms. Nature Publishing Group 1972-12 /pmc/articles/PMC2008667/ /pubmed/4567182 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Beamish, M. R.
Jones, P. Ashley
Trevett, D.
Evans, I. Howell
Jacobs, A.
Iron Metabolism in Hodgkin's Disease
title Iron Metabolism in Hodgkin's Disease
title_full Iron Metabolism in Hodgkin's Disease
title_fullStr Iron Metabolism in Hodgkin's Disease
title_full_unstemmed Iron Metabolism in Hodgkin's Disease
title_short Iron Metabolism in Hodgkin's Disease
title_sort iron metabolism in hodgkin's disease
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008667/
https://www.ncbi.nlm.nih.gov/pubmed/4567182
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