Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice

Washed lymphocytes from immunized rats showed no reaction against mouse plasmacytoma 5563 in vivo or in vitro. Cell-free lymph from immunized rats was shown to be cytotoxic to the tumour cells in vitro. This effect we have shown to be solely in the 19s fraction after Sephadex G-200 separation. This...

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Detalles Bibliográficos
Autores principales: Fakhri, O., Hobbs, J. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008713/
https://www.ncbi.nlm.nih.gov/pubmed/5503607
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author Fakhri, O.
Hobbs, J. R.
author_facet Fakhri, O.
Hobbs, J. R.
author_sort Fakhri, O.
collection PubMed
description Washed lymphocytes from immunized rats showed no reaction against mouse plasmacytoma 5563 in vivo or in vitro. Cell-free lymph from immunized rats was shown to be cytotoxic to the tumour cells in vitro. This effect we have shown to be solely in the 19s fraction after Sephadex G-200 separation. This 19s fraction conferred partial protection to tumour bearing mice when given shortly after transplantation, but had negligible effect against late well established tumour.
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spelling pubmed-20087132009-09-10 Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice Fakhri, O. Hobbs, J. R. Br J Cancer Articles Washed lymphocytes from immunized rats showed no reaction against mouse plasmacytoma 5563 in vivo or in vitro. Cell-free lymph from immunized rats was shown to be cytotoxic to the tumour cells in vitro. This effect we have shown to be solely in the 19s fraction after Sephadex G-200 separation. This 19s fraction conferred partial protection to tumour bearing mice when given shortly after transplantation, but had negligible effect against late well established tumour. Nature Publishing Group 1970-12 /pmc/articles/PMC2008713/ /pubmed/5503607 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Fakhri, O.
Hobbs, J. R.
Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title_full Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title_fullStr Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title_full_unstemmed Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title_short Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice
title_sort studies of the rat immune response to plasmacytoma 5563 in c3h mice
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008713/
https://www.ncbi.nlm.nih.gov/pubmed/5503607
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