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Pulmonary Adenomata Induced by Carcinogen Treatment in Organ Culture. Influence of Increasing Amounts of Carcinogen

Explants of lung from 1 month old inbred BALB/c mice were cultured in vitro for 4 days with 3-methylcholanthrene added to the culture medium at various dose levels. They were subsequently implanted subcutaneously into 6-week-old mice of the same strain. Lung adenomata appeared in a high proportion o...

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Detalles Bibliográficos
Autores principales: Davies, R. F., Major, I. R., Aberdeen, Elizabeth R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008714/
https://www.ncbi.nlm.nih.gov/pubmed/5503603
Descripción
Sumario:Explants of lung from 1 month old inbred BALB/c mice were cultured in vitro for 4 days with 3-methylcholanthrene added to the culture medium at various dose levels. They were subsequently implanted subcutaneously into 6-week-old mice of the same strain. Lung adenomata appeared in a high proportion of explants.