Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis

Adrenocortical activity has been assessed in patients with inoperable carcinoma of the bronchus or with disseminated malignant disease of other organs. The mean basal plasma cortisol level was higher in the former than in the latter and both were higher than the controls. Each had abnormally high mi...

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Detalles Bibliográficos
Autores principales: Bishop, M. C., Ross, E. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008721/
https://www.ncbi.nlm.nih.gov/pubmed/5503599
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author Bishop, M. C.
Ross, E. J.
author_facet Bishop, M. C.
Ross, E. J.
author_sort Bishop, M. C.
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description Adrenocortical activity has been assessed in patients with inoperable carcinoma of the bronchus or with disseminated malignant disease of other organs. The mean basal plasma cortisol level was higher in the former than in the latter and both were higher than the controls. Each had abnormally high midnight levels, particularly those with oat cell carcinoma of the bronchus. After the administration of a single dose of dexamethasone both groups suppressed poorly compared with the controls. Failure to suppress was associated with a poor prognosis.
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spelling pubmed-20087212009-09-10 Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis Bishop, M. C. Ross, E. J. Br J Cancer Articles Adrenocortical activity has been assessed in patients with inoperable carcinoma of the bronchus or with disseminated malignant disease of other organs. The mean basal plasma cortisol level was higher in the former than in the latter and both were higher than the controls. Each had abnormally high midnight levels, particularly those with oat cell carcinoma of the bronchus. After the administration of a single dose of dexamethasone both groups suppressed poorly compared with the controls. Failure to suppress was associated with a poor prognosis. Nature Publishing Group 1970-12 /pmc/articles/PMC2008721/ /pubmed/5503599 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Bishop, M. C.
Ross, E. J.
Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title_full Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title_fullStr Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title_full_unstemmed Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title_short Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
title_sort adrenocortical activity in disseminated malignant disease in relation to prognosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008721/
https://www.ncbi.nlm.nih.gov/pubmed/5503599
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AT rossej adrenocorticalactivityindisseminatedmalignantdiseaseinrelationtoprognosis

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