Fine Structure of an Oat Cell Carcinoma of the Lung Associated with Ectopic ACTH Syndrome

Electron-microscopic examination of an oat-cell carcinoma associated with the ectopic ACTH syndrome demonstrated characteristic cytoplasmic granules of 60-240 nm. diameter, consisting of a dense central core separated by a clear halo from an outer investing membrane. Comparison with previously exami...

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Detalles Bibliográficos
Autores principales: Corrin, B., McMillan, Mary
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1970
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008727/
https://www.ncbi.nlm.nih.gov/pubmed/4323225
Descripción
Sumario:Electron-microscopic examination of an oat-cell carcinoma associated with the ectopic ACTH syndrome demonstrated characteristic cytoplasmic granules of 60-240 nm. diameter, consisting of a dense central core separated by a clear halo from an outer investing membrane. Comparison with previously examined non-secretory oat-cell carcinomas showed the granules to be more numerous in the present case. They are considered to represent secretory activity in the tumour. IMAGES:

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