Ferritinaemia in Leukaemia and Hodgkin's Disease

The serum ferritin concentration is increased in both acute myeloblastic leukaemia and Hodgkin's disease. In acute leukaemia the mean concentration is about ten times the normal level and is associated with a high concentration of transferrin-bound iron. In Hodgkin's disease abnormal ferri...

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Detalles Bibliográficos
Autores principales: Jones, P. A. E., Miller, F. M., Worwood, M., Jacobs, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008776/
https://www.ncbi.nlm.nih.gov/pubmed/4511989
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author Jones, P. A. E.
Miller, F. M.
Worwood, M.
Jacobs, A.
author_facet Jones, P. A. E.
Miller, F. M.
Worwood, M.
Jacobs, A.
author_sort Jones, P. A. E.
collection PubMed
description The serum ferritin concentration is increased in both acute myeloblastic leukaemia and Hodgkin's disease. In acute leukaemia the mean concentration is about ten times the normal level and is associated with a high concentration of transferrin-bound iron. In Hodgkin's disease abnormal ferritinaemia is associated with a low concentration of transferrin-bound iron and appears to result from a block of reticuloendothelial iron release. Increased concentrations of circulating ferritin have also been observed in a few cases of chronic leukaemia and myelomatosis.
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spelling pubmed-20087762009-09-10 Ferritinaemia in Leukaemia and Hodgkin's Disease Jones, P. A. E. Miller, F. M. Worwood, M. Jacobs, A. Br J Cancer Articles The serum ferritin concentration is increased in both acute myeloblastic leukaemia and Hodgkin's disease. In acute leukaemia the mean concentration is about ten times the normal level and is associated with a high concentration of transferrin-bound iron. In Hodgkin's disease abnormal ferritinaemia is associated with a low concentration of transferrin-bound iron and appears to result from a block of reticuloendothelial iron release. Increased concentrations of circulating ferritin have also been observed in a few cases of chronic leukaemia and myelomatosis. Nature Publishing Group 1973-03 /pmc/articles/PMC2008776/ /pubmed/4511989 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Jones, P. A. E.
Miller, F. M.
Worwood, M.
Jacobs, A.
Ferritinaemia in Leukaemia and Hodgkin's Disease
title Ferritinaemia in Leukaemia and Hodgkin's Disease
title_full Ferritinaemia in Leukaemia and Hodgkin's Disease
title_fullStr Ferritinaemia in Leukaemia and Hodgkin's Disease
title_full_unstemmed Ferritinaemia in Leukaemia and Hodgkin's Disease
title_short Ferritinaemia in Leukaemia and Hodgkin's Disease
title_sort ferritinaemia in leukaemia and hodgkin's disease
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008776/
https://www.ncbi.nlm.nih.gov/pubmed/4511989
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AT millerfm ferritinaemiainleukaemiaandhodgkinsdisease
AT worwoodm ferritinaemiainleukaemiaandhodgkinsdisease
AT jacobsa ferritinaemiainleukaemiaandhodgkinsdisease

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