Local Immunoglobulin Production in Breast Cancer

Immunoglobulin levels (IgA, IgG, IgM) have been estimated in protein extracts of 55 malignant and 20 benign tumours of the breast, and in 17 normal tissues from a cancer bearing breast. IgA and IgG were significantly reduced in cancer compared with both benign and normal tissues but IgM, detected in...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, M. Maureen, Bass, Eleanor M., Wallace, I. W. J., Stevenson, Ann
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008783/
https://www.ncbi.nlm.nih.gov/pubmed/4739847
_version_ 1782135986025660416
author Roberts, M. Maureen
Bass, Eleanor M.
Wallace, I. W. J.
Stevenson, Ann
author_facet Roberts, M. Maureen
Bass, Eleanor M.
Wallace, I. W. J.
Stevenson, Ann
author_sort Roberts, M. Maureen
collection PubMed
description Immunoglobulin levels (IgA, IgG, IgM) have been estimated in protein extracts of 55 malignant and 20 benign tumours of the breast, and in 17 normal tissues from a cancer bearing breast. IgA and IgG were significantly reduced in cancer compared with both benign and normal tissues but IgM, detected in only a third of tumours, was significantly increased. Total immunoglobulin levels and IgG in the malignant tumours correlated with plasma cell infiltration. The menstrual status of the patient had no influence on these findings.
format Text
id pubmed-2008783
institution National Center for Biotechnology Information
language English
publishDate 1973
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20087832009-09-10 Local Immunoglobulin Production in Breast Cancer Roberts, M. Maureen Bass, Eleanor M. Wallace, I. W. J. Stevenson, Ann Br J Cancer Articles Immunoglobulin levels (IgA, IgG, IgM) have been estimated in protein extracts of 55 malignant and 20 benign tumours of the breast, and in 17 normal tissues from a cancer bearing breast. IgA and IgG were significantly reduced in cancer compared with both benign and normal tissues but IgM, detected in only a third of tumours, was significantly increased. Total immunoglobulin levels and IgG in the malignant tumours correlated with plasma cell infiltration. The menstrual status of the patient had no influence on these findings. Nature Publishing Group 1973-04 /pmc/articles/PMC2008783/ /pubmed/4739847 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Roberts, M. Maureen
Bass, Eleanor M.
Wallace, I. W. J.
Stevenson, Ann
Local Immunoglobulin Production in Breast Cancer
title Local Immunoglobulin Production in Breast Cancer
title_full Local Immunoglobulin Production in Breast Cancer
title_fullStr Local Immunoglobulin Production in Breast Cancer
title_full_unstemmed Local Immunoglobulin Production in Breast Cancer
title_short Local Immunoglobulin Production in Breast Cancer
title_sort local immunoglobulin production in breast cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008783/
https://www.ncbi.nlm.nih.gov/pubmed/4739847
work_keys_str_mv AT robertsmmaureen localimmunoglobulinproductioninbreastcancer
AT basseleanorm localimmunoglobulinproductioninbreastcancer
AT wallaceiwj localimmunoglobulinproductioninbreastcancer
AT stevensonann localimmunoglobulinproductioninbreastcancer

Ejemplares similares