The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms

The frequency of M-components was studied by agar gel electrophoresis in sera from 807 patients, 467 (57%) females and 340 (43%) males with histologically proven solid malignant neoplasms. M-components were found in the sera of 40 male and 20 female patients. Apart from two known cases of multiple m...

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Detalles Bibliográficos
Autores principales: Talerman, A., Haije, W. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008789/
https://www.ncbi.nlm.nih.gov/pubmed/4633840
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author Talerman, A.
Haije, W. G.
author_facet Talerman, A.
Haije, W. G.
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description The frequency of M-components was studied by agar gel electrophoresis in sera from 807 patients, 467 (57%) females and 340 (43%) males with histologically proven solid malignant neoplasms. M-components were found in the sera of 40 male and 20 female patients. Apart from two known cases of multiple myeloma and one case of Waldenström's macroglobulinaemia, none of the patients were found to be suffering from these diseases. The frequency of M-components increased with age, and this was more evident in males. Twenty-two of 60 patients with M-components did not exhibit abnormalities on immunoelectrophoresis. Of the 35 remaining patients, 27 had an abnormal component of the IgG class, 6 of the IgA and 2 of the IgM class. M-components were found in the sera of patients with a wide variety of neoplasms. There appeared to be no evidence of an increased frequency of M-components in the sera of patients with solid malignant neoplasms compared with normal adult population. IMAGES:
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spelling pubmed-20087892009-09-10 The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms Talerman, A. Haije, W. G. Br J Cancer Articles The frequency of M-components was studied by agar gel electrophoresis in sera from 807 patients, 467 (57%) females and 340 (43%) males with histologically proven solid malignant neoplasms. M-components were found in the sera of 40 male and 20 female patients. Apart from two known cases of multiple myeloma and one case of Waldenström's macroglobulinaemia, none of the patients were found to be suffering from these diseases. The frequency of M-components increased with age, and this was more evident in males. Twenty-two of 60 patients with M-components did not exhibit abnormalities on immunoelectrophoresis. Of the 35 remaining patients, 27 had an abnormal component of the IgG class, 6 of the IgA and 2 of the IgM class. M-components were found in the sera of patients with a wide variety of neoplasms. There appeared to be no evidence of an increased frequency of M-components in the sera of patients with solid malignant neoplasms compared with normal adult population. IMAGES: Nature Publishing Group 1973-04 /pmc/articles/PMC2008789/ /pubmed/4633840 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Talerman, A.
Haije, W. G.
The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title_full The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title_fullStr The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title_full_unstemmed The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title_short The Frequency of M-components in Sera of Patients with Solid Malignant Neoplasms
title_sort frequency of m-components in sera of patients with solid malignant neoplasms
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008789/
https://www.ncbi.nlm.nih.gov/pubmed/4633840
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