BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells

Pulmonary growths produced by intravenous injection of methycholanthrene-induced sarcoma cells were controlled or suppressed by specific immunostimulation with BCG-sarcoma cell inocula at subcutaneous sites or by intravenous treatment with BCG alone. The response was dependent upon the immunogenicit...

Descripción completa

Detalles Bibliográficos
Autores principales: Baldwin, R. W., Pimm, M. V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008826/
https://www.ncbi.nlm.nih.gov/pubmed/4686177
_version_ 1782135993573310464
author Baldwin, R. W.
Pimm, M. V.
author_facet Baldwin, R. W.
Pimm, M. V.
author_sort Baldwin, R. W.
collection PubMed
description Pulmonary growths produced by intravenous injection of methycholanthrene-induced sarcoma cells were controlled or suppressed by specific immunostimulation with BCG-sarcoma cell inocula at subcutaneous sites or by intravenous treatment with BCG alone. The response was dependent upon the immunogenicity of the treated tumour so that in comparison, intravenous injection of BCG enhanced rather than suppressed pulmonary growths of transferred cells of several weakly immunogenic tumours including a spontaneously arising sarcoma and an epithelioma as well as a carcinogen-induced mammary carcinoma.
format Text
id pubmed-2008826
institution National Center for Biotechnology Information
language English
publishDate 1973
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20088262009-09-10 BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells Baldwin, R. W. Pimm, M. V. Br J Cancer Articles Pulmonary growths produced by intravenous injection of methycholanthrene-induced sarcoma cells were controlled or suppressed by specific immunostimulation with BCG-sarcoma cell inocula at subcutaneous sites or by intravenous treatment with BCG alone. The response was dependent upon the immunogenicity of the treated tumour so that in comparison, intravenous injection of BCG enhanced rather than suppressed pulmonary growths of transferred cells of several weakly immunogenic tumours including a spontaneously arising sarcoma and an epithelioma as well as a carcinogen-induced mammary carcinoma. Nature Publishing Group 1973-01 /pmc/articles/PMC2008826/ /pubmed/4686177 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Baldwin, R. W.
Pimm, M. V.
BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title_full BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title_fullStr BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title_full_unstemmed BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title_short BCG Immunotherapy of Pulmonary Growths from Intravenously Transferred Rat Tumour Cells
title_sort bcg immunotherapy of pulmonary growths from intravenously transferred rat tumour cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008826/
https://www.ncbi.nlm.nih.gov/pubmed/4686177
work_keys_str_mv AT baldwinrw bcgimmunotherapyofpulmonarygrowthsfromintravenouslytransferredrattumourcells
AT pimmmv bcgimmunotherapyofpulmonarygrowthsfromintravenouslytransferredrattumourcells

Ejemplares similares