Immunological Properties of Neoplastic Neural Tissues

The results are presented of the examination of 28 neoplasms from the nervous system for an organ-specific antigenic material demonstrated in glial cells and myelin, using gel diffusion, immunocytotoxicity and immunofluorescence techniques. The antigenic material was demonstrable in benign gliomas a...

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Autores principales: Wickremesinghe, H. R., Yates, P. O.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1971
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008866/
https://www.ncbi.nlm.nih.gov/pubmed/5004175
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author Wickremesinghe, H. R.
Yates, P. O.
author_facet Wickremesinghe, H. R.
Yates, P. O.
author_sort Wickremesinghe, H. R.
collection PubMed
description The results are presented of the examination of 28 neoplasms from the nervous system for an organ-specific antigenic material demonstrated in glial cells and myelin, using gel diffusion, immunocytotoxicity and immunofluorescence techniques. The antigenic material was demonstrable in benign gliomas and in those of low-grade malignancy, but not in the more malignant gliomas and non-gliomatous neoplasia. The implications of the loss of specific antigenic material with reference to cell structure and function, and some fallacies in the interpretation of the significance of tissue specific antigen in carcinogenesis are discussed. IMAGES:
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spelling pubmed-20088662009-09-10 Immunological Properties of Neoplastic Neural Tissues Wickremesinghe, H. R. Yates, P. O. Br J Cancer Articles The results are presented of the examination of 28 neoplasms from the nervous system for an organ-specific antigenic material demonstrated in glial cells and myelin, using gel diffusion, immunocytotoxicity and immunofluorescence techniques. The antigenic material was demonstrable in benign gliomas and in those of low-grade malignancy, but not in the more malignant gliomas and non-gliomatous neoplasia. The implications of the loss of specific antigenic material with reference to cell structure and function, and some fallacies in the interpretation of the significance of tissue specific antigen in carcinogenesis are discussed. IMAGES: Nature Publishing Group 1971-12 /pmc/articles/PMC2008866/ /pubmed/5004175 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Wickremesinghe, H. R.
Yates, P. O.
Immunological Properties of Neoplastic Neural Tissues
title Immunological Properties of Neoplastic Neural Tissues
title_full Immunological Properties of Neoplastic Neural Tissues
title_fullStr Immunological Properties of Neoplastic Neural Tissues
title_full_unstemmed Immunological Properties of Neoplastic Neural Tissues
title_short Immunological Properties of Neoplastic Neural Tissues
title_sort immunological properties of neoplastic neural tissues
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008866/
https://www.ncbi.nlm.nih.gov/pubmed/5004175
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