The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments

In two separate experiments benzopyrene has been painted regularly on the backs of mice at difference dose levels. It has been shown that the incidence rate of both tumours and infiltrating carcinomas can be taken as proportional to d(2)(t — w)(k) where t is time from first application, w and k are...

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Detalles Bibliográficos
Autores principales: Lee, P. N., O'Neill, J. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1971
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008877/
https://www.ncbi.nlm.nih.gov/pubmed/5144539
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author Lee, P. N.
O'Neill, J. A.
author_facet Lee, P. N.
O'Neill, J. A.
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description In two separate experiments benzopyrene has been painted regularly on the backs of mice at difference dose levels. It has been shown that the incidence rate of both tumours and infiltrating carcinomas can be taken as proportional to d(2)(t — w)(k) where t is time from first application, w and k are constants independent of dose, and d is the applied dose.
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spelling pubmed-20088772009-09-10 The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments Lee, P. N. O'Neill, J. A. Br J Cancer Articles In two separate experiments benzopyrene has been painted regularly on the backs of mice at difference dose levels. It has been shown that the incidence rate of both tumours and infiltrating carcinomas can be taken as proportional to d(2)(t — w)(k) where t is time from first application, w and k are constants independent of dose, and d is the applied dose. Nature Publishing Group 1971-12 /pmc/articles/PMC2008877/ /pubmed/5144539 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Lee, P. N.
O'Neill, J. A.
The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title_full The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title_fullStr The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title_full_unstemmed The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title_short The Effect Both of Time and Dose Applied on Tumour Incidence Rate in Benzopyrene Skin Painting Experiments
title_sort effect both of time and dose applied on tumour incidence rate in benzopyrene skin painting experiments
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008877/
https://www.ncbi.nlm.nih.gov/pubmed/5144539
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