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Methotrexate in Liver and Bile after Intravenous Dosage in Man
Measurements of methotrexate have been made in the liver and plasma of 4 patients and in the bile and plasma of 1 patient receiving [(3)H]methotrexate. Projections from a theoretical model of concentration of methotrexate in liver are confirmed but projections of biliary excretion are not.
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1973
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008933/ https://www.ncbi.nlm.nih.gov/pubmed/4783160 |
| _version_ | 1782136013509885952 |
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| author | Creaven, P. J. Hansen, H. H. Alford, D. A. Allen, L. M. |
| author_facet | Creaven, P. J. Hansen, H. H. Alford, D. A. Allen, L. M. |
| author_sort | Creaven, P. J. |
| collection | PubMed |
| description | Measurements of methotrexate have been made in the liver and plasma of 4 patients and in the bile and plasma of 1 patient receiving [(3)H]methotrexate. Projections from a theoretical model of concentration of methotrexate in liver are confirmed but projections of biliary excretion are not. |
| format | Text |
| id | pubmed-2008933 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1973 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-20089332009-09-10 Methotrexate in Liver and Bile after Intravenous Dosage in Man Creaven, P. J. Hansen, H. H. Alford, D. A. Allen, L. M. Br J Cancer Articles Measurements of methotrexate have been made in the liver and plasma of 4 patients and in the bile and plasma of 1 patient receiving [(3)H]methotrexate. Projections from a theoretical model of concentration of methotrexate in liver are confirmed but projections of biliary excretion are not. Nature Publishing Group 1973-12 /pmc/articles/PMC2008933/ /pubmed/4783160 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Articles Creaven, P. J. Hansen, H. H. Alford, D. A. Allen, L. M. Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title | Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title_full | Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title_fullStr | Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title_full_unstemmed | Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title_short | Methotrexate in Liver and Bile after Intravenous Dosage in Man |
| title_sort | methotrexate in liver and bile after intravenous dosage in man |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008933/ https://www.ncbi.nlm.nih.gov/pubmed/4783160 |
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