The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases

Mice were implanted with a lymphosarcoma on either the thorax or leg. Some of these tumours were given a single dose of 240 kV x-rays on reaching a predetermined size, whilst others were left unirradiated. Metastases developed in specific lymph nodes, depending on the position of the transplanted tu...

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Detalles Bibliográficos
Autores principales: Sheldon, P. W., Fowler, J. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008934/
https://www.ncbi.nlm.nih.gov/pubmed/4801677
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author Sheldon, P. W.
Fowler, J. F.
author_facet Sheldon, P. W.
Fowler, J. F.
author_sort Sheldon, P. W.
collection PubMed
description Mice were implanted with a lymphosarcoma on either the thorax or leg. Some of these tumours were given a single dose of 240 kV x-rays on reaching a predetermined size, whilst others were left unirradiated. Metastases developed in specific lymph nodes, depending on the position of the transplanted tumour, and were larger if the tumour had been irradiated than if not. The growth rate of metastases in the ipsilateral axillary lymph node was faster than that of the transplanted tumours, irrespective of the radiation dose the tumour had received.
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spelling pubmed-20089342009-09-10 The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases Sheldon, P. W. Fowler, J. F. Br J Cancer Articles Mice were implanted with a lymphosarcoma on either the thorax or leg. Some of these tumours were given a single dose of 240 kV x-rays on reaching a predetermined size, whilst others were left unirradiated. Metastases developed in specific lymph nodes, depending on the position of the transplanted tumour, and were larger if the tumour had been irradiated than if not. The growth rate of metastases in the ipsilateral axillary lymph node was faster than that of the transplanted tumours, irrespective of the radiation dose the tumour had received. Nature Publishing Group 1973-12 /pmc/articles/PMC2008934/ /pubmed/4801677 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Sheldon, P. W.
Fowler, J. F.
The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title_full The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title_fullStr The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title_full_unstemmed The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title_short The Effect of Irradiating a Transplanted Murine Lymphosarcoma on the Subsequent Development of Metastases
title_sort effect of irradiating a transplanted murine lymphosarcoma on the subsequent development of metastases
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008934/
https://www.ncbi.nlm.nih.gov/pubmed/4801677
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