The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)

The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU) injected subcutaneously at 3 different dose levels in European hamsters were studied. DMN induced malignant haemangioendotheliomata of the liver and kidney, hepatocellular carcinomata and, in one animal, a cholangiocel...

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Autores principales: Mohr, U., Haas, H., Hilfrich, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009008/
https://www.ncbi.nlm.nih.gov/pubmed/4369271
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author Mohr, U.
Haas, H.
Hilfrich, J.
author_facet Mohr, U.
Haas, H.
Hilfrich, J.
author_sort Mohr, U.
collection PubMed
description The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU) injected subcutaneously at 3 different dose levels in European hamsters were studied. DMN induced malignant haemangioendotheliomata of the liver and kidney, hepatocellular carcinomata and, in one animal, a cholangiocellular carcinoma. The effect of NMU was localized at the site of administration and resulted in subcutaneous fibrosarcomata, carcinosarcomata or epidermal carcinomata. IMAGES:
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spelling pubmed-20090082009-09-10 The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.) Mohr, U. Haas, H. Hilfrich, J. Br J Cancer Articles The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU) injected subcutaneously at 3 different dose levels in European hamsters were studied. DMN induced malignant haemangioendotheliomata of the liver and kidney, hepatocellular carcinomata and, in one animal, a cholangiocellular carcinoma. The effect of NMU was localized at the site of administration and resulted in subcutaneous fibrosarcomata, carcinosarcomata or epidermal carcinomata. IMAGES: Nature Publishing Group 1974-05 /pmc/articles/PMC2009008/ /pubmed/4369271 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Mohr, U.
Haas, H.
Hilfrich, J.
The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title_full The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title_fullStr The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title_full_unstemmed The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title_short The Carcinogenic Effects of Dimethylnitrosamine and Nitrosomethylurea in European Hamsters (Cricetus cricetus L.)
title_sort carcinogenic effects of dimethylnitrosamine and nitrosomethylurea in european hamsters (cricetus cricetus l.)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009008/
https://www.ncbi.nlm.nih.gov/pubmed/4369271
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